Nepalese Journal of Zoology: central department of zoology

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Proportion of CD4 cells before and after antiretroviral therapy (ART) in people living with HIV/AIDS visiting ART center in Sukraraj Tropical and Infectious Disease Hospital, Teku, Kathmandu, Nepal

S Neupane*, Ms. R Gupta* and Mr. SB Pun**

The present study deals with effect of antiretroviral treatment (ART) and effect of antiretroviral drugs (ARV) on clients attending the ART and Voluntary counseling and testing center (VCT). It is a prospective cross-sectional record-based study. According to the present study, 78 clients have taken ART age up to 54 years. Out of 78 positives, 45 (57.69%) were males and 33 (42.30%) were females. The result showed no significant relationship between age and gender (χ2=4.196, P>0.05) of HIV positives taking ART. Majority of the positives taking ART have CD4 count less than 350 cells/mm3 of blood and no significant relation was found between the number of positives taking ART and the CD4 cell count (χ2=40, P>0.05). Majority of the positives i.e. 38 (48.7%) were on the WHO stage II. Majority of the positives i.e. 55 (70.5%) were given ART regimen containing Zidovudine (ZDV), Lamivudine (3TC) and Nevirapine (NVP).

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